Amyotrophic Lateral Sclerosis

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NDIS

Sep 24, 2020
2 min

FightMND Grant Awards Further Work Into ALS, Other Motor Neuron Diseases

Three grants given researchers at two centres in Australia will advance work into ways of preserving nerve cells in people with ALS

9 views0 comments

Pharnext’s PXT864 Shows Promising Neuroprotective Effects in ALS, Early Study Shows

Jonathan Shar

Aug 28, 2020
3 min

Pharnext’s PXT864 Shows Promising Neuroprotective Effects in ALS, Early Study Shows

Pharnext’s investigational oral combination therapy PXT864 prevents degeneration of motor neurons and their point of contact with...

6 views0 comments

Innovate UK Grant Supports Early Work on Cell Therapy for ALS

Jonathan Shar

Aug 17, 2020
2 min

Innovate UK Grant Supports Early Work on Cell Therapy for ALS

Innovate UK has given a grant to Reflection Therapeutics to help fund research into new ways of protecting the nervous system from motor neu

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AC Immune Working to Move TDP-43 Antibody Into Clinical Testing for ALS

Jonathan Shar

Aug 10, 2020
2 min

AC Immune Working to Move TDP-43 Antibody Into Clinical Testing for ALS

AC Immune is planning to advance its investigational anti-TDP-43 antibody into clinical testing for neurodegenerative diseases, like amyotr

5 views0 comments

Jonathan Shar

Aug 6, 2020
3 min

Aural Analytics To Power Speech-Based Endpoints For The Healey Center ALS Platform Trial at Mass Gen

Aural Analytics, Inc., a privately-held digital health company developing the world’s most advanced suite of clinical-grade speech analytic

3 views0 comments

AstroRx Slows ALS Progression at All Doses Tested, Trial Shows

Jonathan Shar

Aug 5, 2020
4 min

AstroRx Slows ALS Progression at All Doses Tested, Trial Shows

Kadimastem’s cell therapy candidate, AstroRx, significantly lower the rate of disease progression in people with amyotrophic lateral scleros

8 views0 comments

Study Probes Gut Microbiome Alterations, Probiotics in ALS Patients

Jonathan Shar

Aug 3, 2020
3 min

Study Probes Gut Microbiome Alterations, Probiotics in ALS Patients

The gut microbiome in people with amyotrophic lateral sclerosis (ALS) is altered compared to healthy people, which includes an imbalance in

2 views0 comments

Phase 3 Update: Levosimendan Fails to Ease Breathing Problems in ALS Patients

Jonathan Shar

Jul 31, 2020
2 min

Phase 3 Update: Levosimendan Fails to Ease Breathing Problems in ALS Patients

Orion Corporation’s oral therapy levosimendan (ODM-109) failed to preserve lung function and overall functionality in people with amyotrophi

7 views0 comments

Ultrasound Measures of Muscle May Help in Diagnosing, Evaluating ALS

Jonathan Shar

Jul 29, 2020
2 min

Ultrasound Measures of Muscle May Help in Diagnosing, Evaluating ALS

Measurements taken of muscle using ultrasound could be useful in diagnosing or managing amyotrophic lateral sclerosis (ALS), a small study s

4 views0 comments

New FUS Mutation Linked to Aggressive ALS in Teenage Girl

Jonathan Shar

Jul 28, 2020
2 min

New FUS Mutation Linked to Aggressive ALS in Teenage Girl

A new mutation in the FUS gene, which results in a shorter version of the FUS protein that cannot enter form the cell nucleus to work as it

9 views0 comments

Tofersen Safe, Appears to Slow Disease Progression in SOD1 ALS Patients, Phase 1/2 Trial Shows

Jonathan Shar

Jul 23, 2020
5 min

Tofersen Safe, Appears to Slow Disease Progression in SOD1 ALS Patients, Phase 1/2 Trial Shows

Tofersen, Biogen’s investigational therapy for people with familial amyotrophic lateral sclerosis (ALS) caused by SOD1 gene mutations.

6 views0 comments

ALS scientific breakthrough: Diabetes drug metformin shows promise in mouse study for a common type

Jonathan Shar

Jul 22, 2020
0 min

ALS scientific breakthrough: Diabetes drug metformin shows promise in mouse study for a common type

An FDA-approved diabetes drug shows early signs of promise against the most common genetic form of amyotrophic lateral sclerosis.

7 views0 comments

Slower Progression Seen in US Veterans Living Longer Than Disease Norm

Jonathan Shar

Jul 20, 2020
3 min

Slower Progression Seen in US Veterans Living Longer Than Disease Norm

A comparison of amyotrophic lateral sclerosis (ALS) among U.S. military veterans found those who lived the longest with this disease.

4 views0 comments

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